ea0090p728 | Reproductive and Developmental Endocrinology | ECE2023
Hubers Nikki
, Page Christian
, Mbarek Hamdi
, Lambalk Nils
, Ligthart Lannie
, Pool Rene
, Jan Hottenga Jouke
, van Dongen Jenny
, Haberg Siri
, Ehli Erik
, Harris Jennifer
, Willemsen Gonneke
, Boomsma Dorret
Spontaneous dizygotic (DZ) twinning results from a double ovulation and runs in families indicating a genetic component. Endocrinology studies in mothers of DZ twins observed higher levels of follicle stimulation hormone (FSH) and FSHB was, together with SMAD3, one the first loci identified as genome wide significant in genome-wide association studies (GWAS) of having DZ twins. Several additional loci were recently found that indicate genes involved with fema...